Preventative Effects of Caffeic Acid Phenyl Ester on Cadmium Intoxication Induced Hematological and Blood Coagulation Disturbances and Hepatorenal Damage in Rats

Table 3

Antioxidant and lipid peroxidation status in serum and hepatorenal tissues.

Group	GSH (μmol/mg protein)			SOD (U/mg protein)			TBARS (nmol/mg protein)
	Serum	Liver	Kidney	Serum	Liver	Kidney	Serum	Liver	Kidney
Control; (𝑛=10)	13.7±3.1	69.9±7.3	57.7±9.2	3.8±0.6	289.5±37.3	267.7±23.4	27.4±4.2	48.6±6.2	37.4±5.9
Cd; (𝑛=15)	4.7 ± 0.9*	11.7 ± 1.2*	13.74±1.7 *	1.2 ± 0.2*	64.8 ± 8.2*	71.5 ± 6.7*	116.2 ± 23.4*	1019.5 ± 195.9*	1113.3 ± 195.9*
Cd + CAPE; (𝑛=15)	12.2 ± 1.2^#	75.9 ± 11.4^#	68.7 ± 10.2^#	3.3 ± 0.8^#	305.3 ± 50.5^#	311.5 ± 47.8^#	36.74 ± 5.8^#	87.2 ± 14.6^#	118.6 ± 23.29^#

The values are presented as means ± SD. (Cd) cadmium, (CAPE) caffeic acid phenyl ester, (GSH) total glutathione, (SOD) superoxide dismutase, and (TBARS) thiobarbituric acid reactive substances. *𝑃<0.05 versus control group; ^#𝑃<0.05 versus Cd group.