Table of Contents
ISRN Organic Chemistry
Volume 2014, Article ID 767954, 5 pages
Research Article

A Facile Stereoselective Total Synthesis of (R)-Rugulactone

1Polymer Science and Engineering Division, National Chemical Laboratory, Pashan, Pune 411 008, India
2Bharati Vidyapeeth University, Advanced Research Centre in Pharmaceutical Sciences & Applied Chemistry, Poona College of Pharmacy, Erandwane, Pune 411038, India

Received 15 December 2013; Accepted 6 January 2014; Published 30 March 2014

Academic Editors: A. Barbero and F. L. Van Delft

Copyright © 2014 B. Narasimha Reddy and R. P. Singh. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


An efficient and novel synthesis of (R)-rugulactone has been achieved employing Sharpless asymmetric epoxidation of allyl alcohols followed by selective hydride reduction of epoxy alcohols and olefin cross metathesis reactions.