The Role of Androgen Hormones in Early Follicular Development

Table 1

Profile of mRNA expression and of AR protein in the different follicular classes.

Lenie and Smitz, 2009 [20]

Juengel et al., 2006 [42]

Cárdenas and Pope, 2002 [43]

Salvetti et al., 2012 [41]

Weil et al., 1998 [17]

Chadha et al., 1994 [45]

Animal

Rodent

Sheep

Swine

Cattle

Non-human primate

Human

Final Product

mRNA

Protein

mRNA

Protein

mRNA

Protein

mRNA

Protein

mRNA

Protein

mRNA

Protein

Primordial

X

+

+

+

+

X

X

−

−

X

−

X

Primary

X*

+*

+*

+*

+*

X*

X*

−*

−*

X*

−*

X*

Secondary

X*

+*

+*

−*

+*

X*

X*

+*

+*

X*

−*

X*

Initial antral

X*

+*

+*

−*

+*

X*

X*

++*

+*

X*

+/−*

X*

Final antral

X

+

−

−

+

X

X

++

−

X

+/−

X

Oocyte

X

+++

+

+/−

−

X

X

X

−

X

X

X

Theca

X

+

+

−

−

X

X

+

−

X

+/−

X

Granulosa

X

+

++

+

−

X

X

+

+

X

+/−

X

Legend: (X): not done; (−): No expression; (−/+): Little expression; (+): Low expression; (++): Moderate expression; (+++): Abundant expression.