Research Article

Factor VIII-Related Antigen Detects Phenotypic Change of Sinusoidal to Vascular Endothelium in Hepatic Fibrosis of Elderly Cadavers

Figure 7

(a) Midlobular parenchyma; (b) centrilobular parenchyma. FVIIIRAg-positive sinusoidal endothelial cells are distributed in loose aggregates in the parenchyma. The immune deposits (brown color) are patchy and discontinuous along the sinusoidal lining. CV = central vein. FVIIIRAg-positive sinusoidal endothelial cells (brown color) are also seen scattered in small groups of a few cells (c) and singly (d) in the lobular parenchyma.
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(a)
839560.fig.007b
(b)
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(c)
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(d)