Factor VIII-Related Antigen Detects Phenotypic Change of Sinusoidal to Vascular Endothelium in Hepatic Fibrosis of Elderly Cadavers
Figure 7
(a) Midlobular parenchyma; (b) centrilobular parenchyma. FVIIIRAg-positive sinusoidal endothelial cells are distributed in loose aggregates in the parenchyma. The immune deposits (brown color) are patchy and discontinuous along the sinusoidal lining. CV = central vein. FVIIIRAg-positive sinusoidal endothelial cells (brown color) are also seen scattered in small groups of a few cells (c) and singly (d) in the lobular parenchyma.