International Scholarly Research Notices / 2014 / Article / Tab 1 / Research Article
Assessment of Leptin Gene Polymorphism rs2060713 in Psoriasis Vulgaris Table 1 (a) Distribution of rs2060713 genotypes among patients with psoriasis vulgaris and controls according to subject’s gender. (b) Distribution of rs2060713 genotypes among patients with psoriasis vulgaris and controls according to subject’s gender and age onset.
(a) Controls Patients
valueOR (95% CI) Male gender Genotype 0.413 C/C 148 (93.1) 144 (90.6) ref. C/T 11 (6.9) 15 (9.4) 1.40 (0.62–3.15) T/T 0 (0.0) 0 (0.0) — Allele 0.423 C 307 (96.5) 303 (95.3) ref. T 11 (3.5) 15 (4.7) 1.38 (0.63–3.06) Female gender Genotype 0.639 C/C 85 (91.4) 93 (89.4) ref. C/T 8 (8.6) 11 (10.6) 1.26 (0.48–3.27) T/T 0 (0.0) 0 (0.0) — Allele 0.648 C 178 (95.7) 197 (94.7) ref. T 8 (4.3) 11 (5.3) 1.24 (0.49–3.16) Total Genotype 0.346 C/C 233 (92.5) 237 (90.1) ref. C/T 19 (7.5) 26 (9.9) 1.35 (0.73–2.50) T/T 0 (0.0) 0 (0.0) — Allele 0.357 C 485 (96.2) 500 (95.1) ref. T 19 (3.8) 26 (4.9) 1.33 (0.73–2.43)
(b) Early onset Late onset Controls Patients
valueOR (95% CI) Controls Patients
valueOR (95% CI) Male gender Genotype 0.140 0.461 C/C 102 (94.4) 96 (88.9) ref. 46 (90.2) 48 (94.1) ref. C/T 6 (5.6) 12 (11.1) 2.12 (0.77–5.89) 5 (9.8) 3 (5.9) 0.58 (0.13–2.55) T/T 0 (0.0) 0 (0.0) — 0 (0.0) 0 (0.0) — Allele 0.149 0.471 C 210 (97.2) 204 (94.4) ref. 97 (95.1) 99 (97.1) ref. T 6 (2.8) 12 (5.6) 2.06 (0.76–5.59) 5 (4.9) 3 (2.9) 0.59 (0.14–2.53) Female gender Genotype 0.725 0.166 C/C 56 (88.9) 59 (90.8) ref. 29 (96.7) 34 (87.2) ref. C/T 7 (11.1) 6 (9.2) 0.81 (0.26–2.57) 1 (3.3) 5 (12.8) 4.27 (0.47–38.62) T/T 0 (0.0) 0 (0.0) — 0 (0.0) 0 (0.0) — Allele 0.732 0.176 C 119 (94.4) 124 (95.4) ref. 59 (98.3) 73 (93.6) ref. T 7 (5.6) 6 (4.6) 0.82 (0.27–2.52) 1 (1.7) 5 (6.4) 4.04 (0.46–35.55) Total Genotype 0.364 0.724 C/C 158 (92.4) 155 (89.6) ref. 75 (92.6) 82 (91.1) ref. C/T 13 (7.6) 18 (10.4) 1.41 (0.67–2.98) 6 (7.4) 8 (8.9) 1.22 (0.40–3.68) T/T 0 (0.0) 0 (0.0) — 0 (0.0) 0 (0.0) — Allele 0.376 0.730 C 329 (96.2) 328 (94.8) ref. 156 (96.3) 172 (95.6) ref. T 13 (3.8) 18 (5.2) 1.39 (0.67–2.22) 6 (3.7) 8 (4.4) 1.21 (0.41–3.56)
