Research Article

Stability-Indicating HPLC Method for the Simultaneous Determination of HIV Tablet Containing Emtricitabine, Tenofovir Disoproxil Fumarate, and Rilpivirine Hydrochloride in Pharmaceutical Dosage Forms

Table 2

Precision results for EMT, TDF, and RPV.

Parameter Sampling interval EMT TDF RPV
Amount present
(mg)
(%)%RSDAmount present
(mg)
(%)%RSDAmount present
(mg)
(%)%RSD

Within-day0 hrs200.77100.380.252299.7299.900.35524.4297.701.592
8 hrs198.6999.340.100299.4899.820.48724.7498.990.181
16 hrs198.3799.180.021299.7899.920.02624.7599.030.442

Between days1st day198.9499.470.063299.6899.890.02524.9199.640.136
2nd day198.6099.300.047299.5499.840.01124.7398.930.207
3rd day197.6698.830.025298.9499.640.10724.5798.310.643