Stability-Indicating HPLC Method for the Simultaneous Determination of HIV Tablet Containing Emtricitabine, Tenofovir Disoproxil Fumarate, and Rilpivirine Hydrochloride in Pharmaceutical Dosage Forms

Table 4

Evaluation data of ruggedness study.

Parameter	EMT			TDF			RPV
	(mg)	(%)	%RSD	(mg)	(%)	%RSD	(mg)	(%)	%RSD
Analyst 1	200.11	100.05	0.64	300.12	100.04	0.112	25.06	100.24	0.132
Analyst 2	200.62	100.31	0.33	298.94	99.64	0.145	24.79	99.16	1.232
Instrument 1	200.18	100.09	0.634	300.29	100.09	0.146	24.81	99.26	0.246
Instrument 2	200.32	100.16	0.357	299.15	99.71	1.133	24.81	99.26	0.241
Lab 1	200.21	100.10	0.470	306.45	102.15	1.059	25.32	101.29	1.976
Lab 2	199.58	99.79	0.354	298.96	99.65	0.103	24.64	98.57	0.103