Research Article

Extractive Spectrophotometric Determination of Tenofovir Disoproxil Fumarate Using Acidic Triphenylmethane Dyes

Table 1

Spectral and analytical parameters for the determination of TDF with triphenylmethane dyes.


λmax (nm)412412413
Beer’s law limits (µg mL−1)4.0–404.0–404.0–40
Molar absorptivity (L Mol−1 cm−1)746250845289
Formation constant (K, M−1)
Sandell’s sensitivity (µg cm−2)0.05490.08060.077
Slope ( )0.01820.01240.0129
Intercept ( )0.04990.08420.1168
Correlation coefficient ( )0.9980.9990.998
Limit of detection (µg mL−1)0.440.440.44
Limit of quantification (µg mL−1)
Regression equation