Table of Contents
International Scholarly Research Notices
Volume 2014, Article ID 876170, 6 pages
http://dx.doi.org/10.1155/2014/876170
Research Article

Antioxidant, Larvicidal, and Cytotoxic Studies on Asplenium aethiopicum (Burm. f.) Becherer

Centre for Plant Biotechnology, Department of Botany, St. Xavier’s College (Autonomous), Palayamkottai, Tamil Nadu 627 002, India

Received 1 March 2014; Revised 5 June 2014; Accepted 17 June 2014; Published 26 August 2014

Academic Editor: Marie Aleth Lacaille-Dubois

Copyright © 2014 Johnson Marimuthu alias Antonysamy et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The present study was intended to determine the antioxidant, larvicidal, and cytotoxic potential of various extracts of Asplenium aethiopicum (Burm. f.) Becherer. Antioxidant potential of the extracts was determined by the DPPH radical scavenging, phosphomolybdenum, and scavenging of H2O2. Larvicidal activity of Asplenium aethiopicum was performed against the fourth instar larvae Culex quinquefasciatus. Cytotoxic activity was analysed in terms of brine shrimp lethality bioassay. The best free radical scavenging activity was exerted by methanolic extract of Asplenium aethiopicum (IC50 91.4 μg/mL) followed by acetone extract (IC50 99.8 μg/mL). Highest larval mortality was observed in the crude acetone extracts of Asplenium aethiopicum against Culex quinquefasciatus (LC50 = 166.6 ppm) followed by methanolic extracts. Acetone extract of Asplenium aethiopicum was found to be most effective at which 50% and 90% mortality of brine shrimp nauplii that occurred were found to be 192.8 and 434.3 ppm, respectively. The results of the present study revealed the antioxidant, larvicidal, and cytotoxic potential of Asplenium aethiopicum.