Table of Contents
International Scholarly Research Notices
Volume 2014 (2014), Article ID 890534, 6 pages
http://dx.doi.org/10.1155/2014/890534
Research Article

Correlation between First and Second Trimester Uterine Artery Doppler Velocimetry and Placental Bed Histopathology

1Department of Obstetrics and Gynecology, Okmeydani Research Hospital, 34382 Istanbul, Turkey
2Department of Obstetrics and Gynecology, Cerrahpasa Faculty of Medicine, Istanbul University, 34098 Istanbul, Turkey
3Department of Pathology, Cerrahpasa Faculty of Medicine, Istanbul University, 34098 Istanbul, Turkey

Received 29 March 2014; Accepted 19 May 2014; Published 13 July 2014

Academic Editor: Gendie Lash

Copyright © 2014 Murat Akbaş et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Aim. To evaluate the relationship between uterine artery Doppler indices and placental bed histopathology independent of clinical outcome. Materials and Methods. Uterine artery measurements were performed to 510 pregnant women who had come for routine antenatal care in 11–14th and 20–24th weeks. Placental bed biopsies from 141 cases were taken during cesarean section. Physiological changes and abnormal placental histology findings were investigated and compared with Doppler findings. Results. 116 biopsies were accepted as adequate biopsy and included in the study. Physiological changes were seen in 100 biopsies. Statistically significant higher PI and RI values in second trimester and higher notch rate in both trimesters were detected in the abnormal placental histology group (). Conclusion. Strong relationship between uterine artery Doppler indices and preeclampsia or intrauterine growth retardation has been shown in previous studies. In our study, we concluded that there is significant relationship between Doppler findings and placental bed histopathology independent of clinical course.