Parameters Associated with Significant Liver Histological Changes in Patients with Chronic Hepatitis B

Table 2

Clinical parameters predictive of advanced liver necroinflammation and fibrosis.

		𝑡 test		Spearman’s correlation		Logistic regression
		𝑡 value	𝑃 value	Correlation coefficient	𝑃 value	OR value	𝑃 value	95% CI for OR
								Lower	Upper
A2-A3	ALB	3.238	0.001	−0.236	0.003	0.888	0.002	0.823	0.958
F2–F4	Age	−3.075	0.002	0.245	0.002	2.113	0.002	1.330	3.356
	ALB	4.099	<0.001	−0.291	<0.001	0.119	0.037	0.016	0.879
	GLOB	−3.282	0.001	0.249	0.002	0.136	0.049	0.019	0.988
	AST	−1.997	0.048	0.235	0.003	1.031	0.011	1.007	1.055
	PLT	4.548	<0.001	−0.383	<0.001	0.991	0.037	0.982	0.999
	PT	−3.355	0.001	0.256	0.001	1.641	<0.001	1.252	2.151