The Severity of Ischemia Varies in Sprague-Dawley Rats from Different Vendors

Figure 1

CT blood flow maps (color bar represents a linear scale from 0 (blue) to 1500 (red) mL/100 g/min). ((a), (e)) Following permanent ipsilateral occlusion and 1 hour of transient common carotid artery occlusion along with the corresponding MRI FSE image. ((b), (f)) obtained at day 1. The hyperintensity in the T₂-weighted FSE images represents regions of tissue damage. The TTC stained histology images ((c), (g)) and the corresponding MRI FSE image ((d), (h)) obtained at day 6 show final lesion size. MRI slices at the 24-hour time point were matched as closely as possible to the 6-day time point.

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