Therapeutic Effects of Acetone Extract of Saraca asoca Seeds on Rats with Adjuvant-Induced Arthritis via Attenuating Inflammatory Responses

Table 4

Changes in left paw diameter and percentage inhibition over time.

Treated groups	Paw size (mm) on day 0	Paw size (mm) on day 7	% Inhibition on day 7	Paw size (mm) on day 14	% Inhibition on day 14	Paw size (mm) on day 21	% Inhibition on day 21
Control	4.37±0.29	6.99±0.17		6.83±0.36		6.77±0.16
Standard indomethacin	4.39±0.17	5.55±0.34^∗∗∗	55.72	4.68±0.21^∗∗∗	88.21	4.4±0.27^∗∗∗	99.58
Acetone extract 300	4.32±0.24	5.92±0.38^∗∗	38.93	5.66±0.44^∗∗∗	45.52	5.44±0.57^∗∗∗	53.33
Acetone extract 500	4.28±0.39	5.62±0.42^∗∗∗	48.85	5.07±0.50^∗∗∗	67.88	4.43±0.40^∗∗∗	93.75

Each value represents mean ± SD of six animals. Statistical analysis was done by one-way ANOVA followed by Dunnett’s 𝑡-test. The values are statistically significant at two levels ^∗∗𝑃<0.01 and ^∗∗∗𝑃<0.001 as compared to arthritic control.