Therapeutic Effects of Acetone Extract of Saraca asoca Seeds on Rats with Adjuvant-Induced Arthritis via Attenuating Inflammatory Responses

Table 5

Changes in left foot joint diameter of rats over time.

Treated groups	Joint size (mm) on day 0	Joint size (mm) on day 7	% Inhibition on day 7	Joint size (mm) on day 14	% Inhibition on day 14	Joint size (mm) on day 21	% Inhibition on day 21
Control	5.18±0.30	6.52±0.18		7.67±0.23		8.12±0.28
Standard; indomethacin	5.13±0.23	5.78±0.26^∗∗∗	51.49	5.31±0.51^∗∗∗	92.77	5.16±0.13^∗∗∗	98.97
Acetone extract 300 (mg/kg)	5.16±0.15	6.35±0.21	11.19	5.98±0.09^∗∗∗	67.06	5.48±0.16^∗∗∗	89.11
Acetone extract 500 (mg/kg)	5.21±0.37	5.87±0.29^∗∗∗	50.75	5.41±0.11^∗∗∗	91.96	5.25±0.32^∗∗∗	98.63

Each value represents mean ± SD of six animals. Statistical analysis was done by one-way ANOVA followed by Dunnett’s t-test. The values are statistically highly significant at ^∗∗∗𝑃<0.001 as compared to control rats.