Plasma Aminothiol Profile and Some of Its Determinants in Apparently Healthy Azorean Subjects

Table 4

Conventional risk factors in aPAP subjects with only low GSH levels (aPAP-1), split by GGT activity.

Parameters	aPAP-1 (129)		P
	nGGT (107)	hGGT (22)
Sex, male (%)	18	41	<0.05
Age (years)	43±10	46±8	NS
Smoking (%)	17	14	NS
Blood pressure (mmHg)
Systolic BP	132±24	143±29	NS
Diastolic BP	80±14	86±19	NS
Hypertension (%)	46	50	NS
BMI (Kg/m^2)
Overweight (%)	33	41	NS
Obese (%)	43	45	NS
Serum lipids (mg/dL)
Triglycerides	118±61	149±70	<0.05
Total cholesterol	212±37	204±25	NS
HDL cholesterol	63±15	53±11	<0.01
LDL cholesterol	128±35	126±23	NS
Hyperlipidemia (%)	68	82	NS
Plasma thiols (μmol/L)
Hcy	8±2	10±2	<0.01
Cys	183±32	205±23	<0.01
Cys-Gly	28±4	28±4	NS
GSH	1.1±0.2	0.9±0.2	<0.001
Plasma vitamins
Folate (ng/mL)	9±4	8±3	NS
Vitamin B12 (pg/mL)	608±381	581±241	NS
Vitamin B6 (nmol/L)	55±33	57±30	NS

nGGT: normal GGT activity; hGGT: high GGT activity; NS: not significant. Values are presented as mean ± SD, except otherwise indicated. Figures in parenthesis are the number of subjects (𝑛). P values denote significant differences between groups.