Research Article
Fast Stability Indicating UPLC Method for Quantitative Analysis of Dronedarone in Pharmaceutical Dosage Form: Force Degradation Study
Table 9
Stress degradation study.
| Stress condition | Time | Purity angle | Purity threshold | % degradation |
| Acid hydrolysis | 5 hr | 0.404 | 0.978 | 3.24 | Base hydrolysis | 1 hr | 1.045 | 12.715 | 24.07 | Oxidation | 1 hr | 3.297 | 11.91 | 18.56 | Thermal | 5 days | 0.573 | 0.944 | 2.37 | Photo | 5 days | 0.764 | 1.363 | 0.48 |
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