Research Article

Phenolic Acids (Gallic and Tannic Acids) Modulate Antioxidant Status and Cisplatin Induced Nephrotoxicity in Rats

Table 2

Effect of tannic acid and gallic acids on antioxidant content level in normal and cisplatin induced nephrotoxicity in rats.

GroupsSODCATGPxGSH

12.01   ±  0.950.18  ±   0.100.21  ±  0.030.24  ±  0.02
21.06b   ±  0.530.09b  ±  0.060.13b   ±  0.000.13b   ±  0.05
31.31c   ±  0.620.16c  ±  0.030.17c   ±  0.030.17c   ±  0.04
41.75c  ±  1.240.16c  ±  0.010.22c   ±  0.050.18c   ±  0.02
52.05  ±  0.730.19  ±   0.020.23  ±  0.080.25  ±  0.02
61.97c  ±  0.930.12c   ±  0.030.16c  ±  0.000.17c   ±  0.03
72.39c  ±  0.210.17c   ±  0.200.23c   ±  0.110.19c   ±  0.00
84.02   ±  0.950.18  ±   0.000.25  ±  0.140.22  ±  0.03

Values represent mean ± standard deviation (). 1: induced control, 2: normal control, 3: 20 mg gallic acid + cisplatin, 4: 40 mg gallic acid + cisplatin, 5: 40 mg gallic acid only, 6: 20 mg tannic acid + cisplatin, 7: 40 mg tannic acid + cisplatin, and 8: 40 mg tannic acid only.
bSignificantly () different from the induced control. cSignificantly () different from the induced control.