Perinatal Outcome in Women with Hypertensive Disorders of Pregnancy: A Retrospective Cohort Study
Table 1
Predictors of perinatal mortality among women with hypertensive disorders of pregnancy (HDP), Ethiopia, 2008–2013.
Variables*
Total
Perinatal deaths (%)
Crude OR (95% CI)
Adjusted OR (95% CI)
Maternal age (years)
15–19
57
31.6
1.0 (0.59–1.85)
20–34
876
31.3
1
35–49
82
36.6
1.2 (0.79–1.98)
Parity
Primigravida
536
27.4
1
1
Multipara (I–IV)
400
34.5
1.4 (1.04–1.80)¥
1.6 (1.12–2.228)‡
Grand multipara (V+)
79
46.8
2.3 (1.44–3.68)‡
2.8 (1.55–4.92)‡
Gestational age (weeks)
Very preterm (<34)
240
63.8
8.1 (5.82–11.22)†
7.7 (5.26–11.20)†
Preterm (34–36)
193
24.9
1.5 (1.04–2.23)¥
1.5 (1.02–2.35)¥
Term + (≥37)
677
17.9
1
1
Number of fetuses
Singleton
920
30.0
1
Twin
190
24.2
0.7 (0.52–1.07)
Antenatal care
Yes
633
22.7
1
1
No
382
40.0
2.3 (1.75–2.97)†
2.0 (1.43–2.67)†
Type of HDP
Preeclampsia
612
26.0
1
1
Eclampsia
346
41.3
2.0 (1.52–2.63)†
4.1 (2.85–6.04)†
Other HDP
57
35.1
1.6 (0.92–2.86)
1.3 (0.65–2.49)
Onset of HDP
Antepartum or before
721
36.2
2.6 (1.57–4.38)†
6.6 (3.40–12.75)†
Intrapartum
183
22.9
1.4 (0.77–2.55)
4.0 (1.99–8.04)†
Postpartum
111
17.1
1
1
HDP severity symptoms
Yes (one or more)
847
32.8
1.3 (0.92–1.92)
None
168
26.2
1
Highest systolic BP
<140 mmHg
60
36.7
1.5 (0.86–2.70)
1.0 (0.44–2.24)
140–159
270
25.9
1
1
160+
685
33.6
1.5 (1.07–1.99)¥
1.0 (0.67–1.55)
Highest diastolic BP
<90 mmHg
39
43.6
2.1 (1.11–4.00)¥
2.3 (0.88–5.79)
90–109
425
24.5
1
1
110+
551
36.5
1.7 (1.33–2.31)†
1.4 (0.96–2.03)
< 0.05; ‡ ≤ 0.001; † < 0.0001. BP: blood pressure. *All variables describe the mother’s condition except gestational age and fetuses number. **Adjusted for parity, gestational age, antenatal care, type of HDP, onset of HDP, highest systolic BP, and highest diastolic BP.
