Incidence and Predictors of Tuberculosis among HIV Positive Children at University of Gondar Referral Hospital, Northwest Ethiopia: A Retrospective Follow-Up Study
Table 2
Cox-regression analysis of predictors of incidence of TB among HIV infected children at University of Gondar Referral Hospital ().
Variables
TB incidence
CHR (95% CI)
AHR (95% CI)
Event
Censored
Sex
Male
28
103
1
Female
26
114
0.84 (0.49–1.43)
Age
<5
18
93
0.87 (0.41–1.84)
5–9
25
77
1.33 (0.65–2.69)
10–14
11
47
1
Residence
Urban
44
187
1
Rural
10
30
1.58 (0.79–3.15)
Family size
2
6
23
1
3-4
31
119
0.94 (0.39–2.26)
5
17
75
0.82 (0.32–2.07)
Parental status
Both parents a live
22
116
1
Paternal orphan
17
39
2.05 (1.09–3.87)
Maternal orphan
7
27
1.26 (0.54–2.95)
Double orphan
5
29
0.90 (0.34–2.38)
Not recorded
3
6
2.27 (0.68–7.58)
WHO clinical stage
I
10
73
1
II
13
59
1.49 (0.65–3.41)
III
23
71
2.06 (0.98–4.33)
IV
8
14
3.66 (1.44–9.29)
Anemia
Anemia
15
27
2.47 (1.36–4.49)
2.23 (1.19–4.15)
No Anemia
39
190
1
Immunodeficiency
Severe
20
77
1.08 (0.62–1.87)
Not severe
34
140
1
ART at initial
Yes
22
90
1.10 (0.64–1.91)
No
32
127
1
IPT
Yes
28
114
1.09 (0.64–1.85)
No
26
118
1
CPT
Yes
53
212
0.82 (0.11–5.96)
No
1
5
1
Past TB treatment history
Yes
11
34
0.82 (0.11–5.96)
No
43
183
1
Functional status
Working
13
88
1
Ambulatory
37
111
2.21 (1.17–4.19)
1.99 (1.04–3.81)
Bedridden
4
18
1.50 (0.49–4.61)
0.92 (0.29–2.92)
Vaccination status
Vaccinated
22
174
1
Not appropriately vaccinated
31
22
7.86 (4.54–13.62)
8.03 (4.61–13.97)
Not recorded
1
21
0.36 (0.05–2.64)
0.42 (0.06–3.15)
Nutritional status
Normal
19
84
1
Stunted
35
133
1.07 (0.61–1.87)
COR = Crude hazard ratio, AOR = Adjusted Hazard Ratio, and CI = confidence interval.
