Table of Contents
International Scholarly Research Notices
Volume 2015 (2015), Article ID 469402, 6 pages
http://dx.doi.org/10.1155/2015/469402
Research Article

Assessment of Tachykinin Receptor 3′ Gene Polymorphism rs3733631 in Rosacea

1Department of Dermatology, Faculty of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece
2Department of Medical Biology, Faculty of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece
3Department of Medical Statistics, Faculty of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece

Received 28 May 2015; Revised 31 August 2015; Accepted 3 September 2015

Academic Editor: Monika Dmitrzak-Weglarz

Copyright © 2015 Anthony Karpouzis et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G. F. Webster, “Rosacea,” Medical Clinics of North America, vol. 93, no. 6, pp. 1183–1194, 2009. View at Publisher · View at Google Scholar · View at Scopus
  2. B. Cribier, “Rosacea under the microscope: characteristic histological findings,” Journal of the European Academy of Dermatology and Venereology, vol. 27, no. 11, pp. 1336–1343, 2013. View at Publisher · View at Google Scholar · View at Scopus
  3. A. A. Aubdool and S. D. Brain, “Neurovascular aspects of skin neurogenic inflammation,” Journal of Investigative Dermatology Symposium Proceedings, vol. 15, no. 1, pp. 33–39, 2011. View at Publisher · View at Google Scholar · View at Scopus
  4. M. Guarrera, A. Parodi, C. Cipriani, C. Divano, and A. Rebora, “Flushing in rosacea: a possible mechanism,” Archives of Dermatological Research, vol. 272, no. 3-4, pp. 311–316, 1982. View at Publisher · View at Google Scholar · View at Scopus
  5. N. Kurkcuoglu and F. Alaybeyi, “Substance P immunoreactivity in rosacea,” Journal of the American Academy of Dermatology, vol. 25, no. 4, pp. 725–726, 1991. View at Publisher · View at Google Scholar · View at Scopus
  6. E. Neumann and A. Frithz, “Capillaropathy and capillaroneogenesis in the pathogenesis of rosacea,” International Journal of Dermatology, vol. 37, no. 4, pp. 263–266, 1998. View at Publisher · View at Google Scholar · View at Scopus
  7. A. H. A. Gomaa, M. Yaar, M. M. K. Eyada, and J. Bhawan, “Lymphangiogenesis and angiogenesis in non-phymatous rosacea,” Journal of Cutaneous Pathology, vol. 34, no. 10, pp. 748–753, 2007. View at Publisher · View at Google Scholar · View at Scopus
  8. D. A. Guzman-Sanchez, Y. Ishiuji, T. Patel, J. Fountain, Y. H. Chan, and G. Yosipovitch, “Enhanced skin blood flow and sensitivity to noxious heat stimuli in papulopustular rosacea,” Journal of the American Academy of Dermatology, vol. 57, no. 5, pp. 800–805, 2007. View at Publisher · View at Google Scholar · View at Scopus
  9. E. C. Sattler, T. Maier, V. S. Hoffmann, J. Hegyi, T. Ruzicka, and C. Berking, “Noninvasive in vivo detection and quantification of Demodex mites by confocal laser scanning microscopy,” British Journal of Dermatology, vol. 167, no. 5, pp. 1042–1047, 2012. View at Publisher · View at Google Scholar · View at Scopus
  10. K. Aroni, E. Tsagroni, N. Kavantzas, E. Patsouris, and E. Ioannidis, “A study of the pathogenesis of Rosacea: how angiogenesis and mast cells may participate in a complex multifactorial process,” Archives of Dermatological Research, vol. 300, no. 3, pp. 125–131, 2008. View at Publisher · View at Google Scholar · View at Scopus
  11. A. M. Khawaja and D. F. Rogers, “Tachykinins: receptor to effector,” International Journal of Biochemistry and Cell Biology, vol. 28, no. 7, pp. 721–738, 1996. View at Publisher · View at Google Scholar · View at Scopus
  12. C. Oschatz, C. Maas, B. Lecher et al., “Mast cells increase vascular permeability by heparin-initiated bradykinin formation in vivo,” Immunity, vol. 34, no. 2, pp. 258–268, 2011. View at Publisher · View at Google Scholar · View at Scopus
  13. J. N. Pennefather, A. Lecci, M. L. Candenas, E. Patak, F. M. Pinto, and C. A. Maggi, “Tachykinins and tachykinin receptors: a growing family,” Life Sciences, vol. 74, no. 12, pp. 1445–1463, 2004. View at Publisher · View at Google Scholar · View at Scopus
  14. T. Marui, I. Funatogawa, S. Koishi et al., “Tachykinin 1 (TAC1) gene SNPs and haplotypes with autism: a case-control study,” Brain & Development, vol. 29, no. 8, pp. 510–513, 2007. View at Publisher · View at Google Scholar · View at Scopus
  15. R. D'Anna, G. Baviera, F. Corrado et al., “Neurokinin B and nitric oxide plasma levels in pre-eclampsia and isolated intrauterine growth restriction,” BJOG: An International Journal of Obstetrics and Gynaecology, vol. 111, no. 10, pp. 1046–1050, 2004. View at Publisher · View at Google Scholar · View at Scopus
  16. N. M. Page, J. Dakour, and D. W. Morrish, “Gene regulation of neurokinin B and its receptor NK3 in late pregnancy and pre-eclampsia,” Molecular Human Reproduction, vol. 12, no. 7, pp. 427–433, 2006. View at Publisher · View at Google Scholar · View at Scopus
  17. A. K. Topaloglu, F. Reimann, M. Guclu et al., “TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction,” Nature Genetics, vol. 41, no. 3, pp. 354–358, 2009. View at Publisher · View at Google Scholar · View at Scopus
  18. M. Fischer, I. Gemende, W. C. Marsch, and P. A. Fischer, “Skin function and skin disorders in Parkinson's disease,” Journal of Neural Transmission, vol. 108, no. 2, pp. 205–213, 2001. View at Publisher · View at Google Scholar · View at Scopus
  19. V. Mesnage, J. L. Houeto, A. M. Bonnet et al., “Neurokinin B, neurotensin, and cannabinoid receptor antagonists and Parkinson disease,” Clinical Neuropharmacology, vol. 27, no. 3, pp. 108–110, 2004. View at Publisher · View at Google Scholar · View at Scopus
  20. M. A. Mittelman-Smith, H. Williams, S. J. Krajewski-Hall, N. T. McMullen, and N. E. Rance, “Role for kisspeptin/neurokininB/dynorphin (KNDy) neurons in cutaneous vasodilatation and the estrogen modulation of body temperature,” Proceedings of the National Academy of Sciences of the United States of America, vol. 109, no. 48, pp. 19846–19851, 2012. View at Publisher · View at Google Scholar · View at Scopus
  21. R. Paus, T. C. Theoharides, and P. C. Arck, “Neuroimmunoendocrine circuitry of the brain-skin connection,” Trends in Immunology, vol. 27, no. 1, pp. 32–39, 2006. View at Publisher · View at Google Scholar · View at Scopus
  22. E. M. J. Peters, P. C. Arck, and R. Paus, “Hair growth inhibition by psychoemotional stress: a mouse model for neural mechanisms in hair growth control,” Experimental Dermatology, vol. 15, no. 1, pp. 1–13, 2006. View at Publisher · View at Google Scholar · View at Scopus
  23. C. Tusset, S. D. Noel, E. B. Trarbach et al., “Mutational analysis of TAC3 and TACR3 genes in patients with idiopathic central pubertal disorders,” Arquivos Brasileiros de Endocrinologia e Metabologia, vol. 56, no. 9, pp. 646–652, 2012. View at Publisher · View at Google Scholar · View at Scopus
  24. X. Xin, J. Zhang, Y. Chang, and Y. Wu, “Association study of TAC3 and TACR3 gene polymorphisms with idiopathic precocious puberty in Chinese girls,” Journal of Pediatric Endocrinology and Metabolism, vol. 28, no. 1-2, pp. 65–71, 2015. View at Publisher · View at Google Scholar · View at Scopus
  25. M. A. de Souza Silva, B. Lenz, A. Rotter et al., “Neurokinin3 receptor as a target to predict and improve learning and memory in the aged organism,” Proceedings of the National Academy of Sciences of the United States of America, vol. 110, no. 37, pp. 15097–15102, 2013. View at Publisher · View at Google Scholar · View at Scopus
  26. T. Foroud, L. F. Wetherill, J. Kramer et al., “The tachykinin receptor 3 is associated with alcohol and cocaine dependence,” Alcoholism: Clinical and Experimental Research, vol. 32, no. 6, pp. 1023–1030, 2008. View at Publisher · View at Google Scholar · View at Scopus
  27. M. Garcia-Barcelo, S. K. King, X. Miao et al., “Application of HapMap data to the evaluation of 8 candidate genes for pediatric slow transit constipation,” Journal of Pediatric Surgery, vol. 42, no. 4, pp. 666–671, 2007. View at Publisher · View at Google Scholar · View at Scopus
  28. S. A. Miller, D. D. Dykes, and H. F. Polesky, “A simple salting out procedure for extracting DNA from human nucleated cells,” Nucleic Acids Research, vol. 16, no. 3, article 1215, 1988. View at Publisher · View at Google Scholar · View at Scopus
  29. T. Jansen, S. Krug, P. Kind, G. Plewig, and G. Messer, “Bsm1 polymorphism of the vitamin D receptor gene in patients with the fulminant course of rosacea,” The Journal of Dermatology, vol. 31, no. 3, pp. 244–246, 2004. View at Publisher · View at Google Scholar
  30. A. C. Yazici, L. Tamer, G. Ikizoglu et al., “GSTM1 and GSTT1 null genotypes as possible heritable factors of rosacea,” Photodermatology Photoimmunology and Photomedicine, vol. 22, no. 4, pp. 208–210, 2006. View at Publisher · View at Google Scholar · View at Scopus
  31. A. L. S. Chang, I. Raber, J. Xu et al., “Assessment of the genetic basis of rosacea by genome-wide association study,” Journal of Investigative Dermatology, vol. 135, pp. 1548–1555, 2015. View at Publisher · View at Google Scholar
  32. E. A. Misch and T. R. Hawn, “Toll-like receptor polymorphisms and susceptibility to human disease,” Clinical Science, vol. 114, no. 5-6, pp. 347–360, 2008. View at Publisher · View at Google Scholar · View at Scopus
  33. F. M. N. Forton, “Papulopustular rosacea, skin immunity and Demodex: pityriasis folliculorum as a missing link,” Journal of the European Academy of Dermatology and Venereology, vol. 26, no. 1, pp. 19–28, 2012. View at Publisher · View at Google Scholar · View at Scopus
  34. J. Schauber, R. A. Dorschner, A. B. Coda et al., “Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism,” The Journal of Clinical Investigation, vol. 117, no. 3, pp. 803–811, 2007. View at Publisher · View at Google Scholar · View at Scopus
  35. M. A. M. van Steensel, S. Badeloe, V. Winnepenninckx, M. Vreeburg, P. M. Steijlen, and M. van Geel, “Granulomatous rosacea and Crohn's disease in a patient homozygous for the Crohn-associated NOD2/CARD15 polymorphism R702W,” Experimental Dermatology, vol. 17, no. 12, pp. 1057–1058, 2008. View at Publisher · View at Google Scholar · View at Scopus
  36. T. Watanabe, A. Kitani, P. J. Murray, and W. Strober, “NOD2 is a negative regulator of Toll-like receptor 2–mediated T helper type 1 responses,” Nature Immunology, vol. 5, no. 8, pp. 800–808, 2004. View at Publisher · View at Google Scholar · View at Scopus