International Scholarly Research Notices / 2015 / Article / Tab 3

Research Article

Toxicity Evaluation of Pũrṇa Cantirotaya Centũram, a Siddha Medicine in Wistar Rats

Table 3

Effect of Pũrṇa Cantirotaya Centũram on relative organ weight (in grams).

OrgansControl (honey)Low dose (2.5 mg/kg b.w.)Mid dose (25 mg/kg b.w.)High dose (50 mg/kg b.w.)

Brain0.938 ± 0.1361.028 ± 0.2120.939 ± 0.1050.865 ± 0.178
Heart0.411 ± 0.0620.419 ± 0.1160.404 ± 0.1130.436 ± 0.098
Lung0.917 ± 0.4730.882 ± 0.3471.027 ± 0.6040.69 ± 0.103
Liver3.875 ± 0.5604.107 ± 0.8143.799 ± 0.8633.986 ± 1.33
Stomach0.507 ± 0.0950.530 ± 0.1010.539 ± 0.1330.527 ± 0.130
Spleen0.9 ± 0.1140.833 ± 0.1900.816 ± 0.1040.975 ± 0.536
Thymus0.402 ± 0.0840.392 ± 0.1310.381 ± 0.0870.386 ± 0.072
Kidney right0.151 ± 0.0340.185 ± 0.0490.15 ± 0.0590.149 ± 0.023
Kidney left0.528 ± 0.1030.55 ± 0.0990.547 ± 0.1340.523 ± 0.150
Testis1.39 ± 0.2191.67 ± 0.3761.55 ± 0.1121.49 ± 0.258
Ovary0.072 ± 0.0190.057 ± 0.0260.058 ± 0.0230.075 ± 0.023

Comparison was made between vehicle control and test groups using the one-way ANOVA test followed by Dunnett’s test. Values are mean ± SD for 10 rats in each group ( < 0.05).