Association between Serum Bilirubin and Estimated Glomerular Filtration Rate among Diabetic Patients
Table 3
Relationship between serum bilirubin categories and risk for reduced eGFR.
Characteristic
Quartiles of serum bilirubin (mg/dL)
value
Q-4 1.01–1.97
Q-3 0.71–1.00
Q-2 0.51–0.70
Q-1 0.13–0.50
eGFR (mL/min/1.73 m2)
59.5 ± 17.9
60.2 ± 18.8
56.0 ± 18.9
48.1 ± 22.9
<0.001
Prevalence of eGFR <60, (%)
51 (40.8)
54 (43.2)
69 (51.1)
73 (58.9)
0.018
Nonadjusted OR (95% CI)
1.00
1.10 (0.67–1.82)
1.52 (0.93–2.48)
2.08 (1.25–3.44)
0.018
Age and gender adjusted OR (95% CI)
1.00
1.23 (0.72–2.09)
1.52 (0.91–2.54)
1.82 (1.07–3.09)
0.133
Multivariate adjusted OR (95% CI)
1.00
1.30 (0.70–2.41)
1.48 (0.81–2.72)
1.53 (0.83–2.81)
0.514
Prevalence of eGFR <45, (%)
22 (17.6)
27 (21.6)
37 (27.4)
53 (42.7)
<0.001
Nonadjusted OR (95% CI)
1.00
1.29 (0.69–2.42)
1.77 (0.97–3.21)
3.50 (1.95–6.25)
<0.001
Age and gender adjusted OR (95% CI)
1.00
1.33 (0.70–2.54)
1.71 (0.93–3.14)
3.12 (1.72–5.65)
0.001
Multivariate adjusted OR (95% CI)
1.00
1.68 (0.78–3.64)
1.74 (0.83–3.65)
3.53 (1.71–7.26)
0.004
CKD: chronic kidney disease: OR: odds ratio; CI: confidence interval. Adjusted for all confounding factors in the stepwise method in Table 2 by multiple logistic regression analysis. Data for triglycerides were skewed and log-transformed for analysis.
