Systematic Review: Adjuvant Chemotherapy for Locally Advanced Rectal Cancer with respect to Stage of Disease

Table 4

Overall survival reported by included studies.

Study	OS
	Stage II				Stage III
	Control	Intervention		Statistical significance	Control	Intervention		Statistical significance
Glimelius et al. 2005 [11]	73%	81%		NS	51%	48%		NS
CCCSGJ 1995 [12]	68.1%	Arm 1; 82.2%; = S	Arm 2; 81.1%; = NS		43.1%	Arm 1; 54.7%; = NS	Arm 2; 62.3%; = S
Fisher et al.; 1988 [13]	57%	80%		S	35%	37%		NS
Kodaira et al. 1998 [15]	75.9%	80.4%		NS	49.1%	53.4%		NS
Hamaguchi et al. 2011 [16]	Not Reported	Not Reported			72.1%	85.3%		S
QUASAR 2007 [17]	76.7%	80.9%		S	Not Reported	Not Reported
Sakamoto et al. 2007 [18]	76.8%	82.4%		S	59.2%	64.1%		S

OS: overall survival, S: significant, and NS: not significant.