Table of Contents
International Scholarly Research Notices
Volume 2015 (2015), Article ID 979404, 5 pages
http://dx.doi.org/10.1155/2015/979404
Research Article

Experience with Clinically Diagnosed Down Syndrome Children Admitted with Diarrhea in an Urban Hospital in Bangladesh

1Dhaka Hospital, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr, b), Mohakhali, Dhaka 1212, Bangladesh
2National Institute of Preventive and Social Medicine (NIPSOM), Mohakhali, Dhaka 1212, Bangladesh
3Centre for Communicable Diseases, icddr, b, Mohakhali, Dhaka 1212, Bangladesh
4Centre for Nutrition & Food Security (CNFS), icddr, b, Mohakhali, Dhaka 1212, Bangladesh

Received 29 January 2015; Revised 8 April 2015; Accepted 21 April 2015

Academic Editor: Csaba Siffel

Copyright © 2015 Rina Das et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

There is lack of information in the medical literature on clinically diagnosed Down syndrome children presenting with diarrhea. Our aim was to describe our experience with Down syndrome patients admitted with diarrhea by evaluating the factors associated with Down syndrome presenting with diarrheal illness. In this retrospective chart analysis, we enrolled all the diarrheal children aged 0–59 months admitted to the Dhaka Hospital of the International Centre for Diarrheal Disease Research, Bangladesh (icddr, b), from March 2011 to February 2013. Down syndrome children with diarrhea constituted cases and randomly selected threefold diarrheal children without Down syndrome constituted controls. Among 8422 enrolled children 32 and 96 were the cases and the controls, respectively. Median age (months) of the cases and the controls was comparable (7.6 (4.0, 15.0) versus 9.0 (5.0, 16.8); ). The cases more often presented with severe acute malnutrition, developmental delay, congenital heart disease, hypothyroidism, sepsis, hypocalcemia, developed hospital acquired infection (HAI) during hospitalization, and required prolonged stay at hospital compared to the controls (for all ). Thus, diarrheal children with clinically diagnosed Down syndrome should be investigated for these simple clinical parameters for their prompt management that may prevent HAI and prolonged hospital stay.