Research Article

Experience with Clinically Diagnosed Down Syndrome Children Admitted with Diarrhea in an Urban Hospital in Bangladesh

Table 1

Characteristics of the cases and the controls admitted to the Intensive Care Unit/High Dependency Unit/Longer Stay Unit of the Dhaka Hospital of icddr, b.

CharacteristicCases Controls OR (95% CI) value
()()(unadjusted)

Male19 (59.4)53 (55.2)1.2 (0.49–2.9)0.840
Age (months) (median, IQR) (range)7.6 (4.0, 15.0)9 (5, 16.8)0.496
Temperature (Celsius) mean ± (SD)37.3 ± 0.937.6 ± 1.070.151
Low socioeconomic status20 (62.5)61 (64.2)0.9 (0.4–2.3)0.960
Formula feeding2 (2.1)2 (1.6)0.440
Developmental delay17 (53.1)3 (3.1)64.5 (13.5–358.5)<0.001
SAM27 (84.4)47 (49.5)5.5 (1.8–17.9)0.001
Dehydrating diarrhea4 (12.5)12 (12.5)1.0 (0.27–0.43)1.00
Pneumonia22 (68)43 (44.8)2.7 (1.1–6.9)0.320
Chronic lung disease1 (3.1)1 (1.0)3.1 (0.0–116.2)0.438
History of repeated RTI1 (3.1)3 (3.1)1.0 (0.1–9.9)1.00
Pulmonary TB2 (6.3)4 (4.2)1.5 (0.2–10.5)0.639
CHD17 (53.1)1 (1.0)107.7 (13.2–2333.2)<0.001
Hypothyroidism3 (9.3)0 (0.0)0.006
Sepsis3 (9.4)0 (0.0)0.010
HAI5 (15.6)2 (2.1)8.7 (1.4–69.2)0.010
Hypocalcemia (mmol/L)4 (80.0)2 (13.3)26 (1.3–1187.8)0.0139
Hypernatremia (mmol/L)3 (16.7)4 (12.9)1.4 (0.2–8.6)0.690
Total duration of hospital stay (median) IQR6 (4.0, 10.0)4 (2.0, 7.0)0.009
Outcome (died)1 (3.1)1 (1.1)0.3 (0.01–11.3)0.410

Figures represent (%) unless indicated otherwise.
OR = odds ratio; CI = confidence interval; IQR = interquartile range; SD = standard deviation.
Hypocalcemia = low serum calcium levels (ref. value = 2.12 to 2.62 mmol/L).
Hypernatremia = elevated sodium level in the blood (ref. value = 135–145 mmol/L).
HAI = hospital acquired infections; CHD = congenital heart disease; RTI = repeated respiratory tract infection; SAM = severe acute malnutrition.