Research Article

Exchange Transfusion for Neonatal Hyperbilirubinemia in Johannesburg, South Africa, from 2006 to 2011

Table 2

Comparison of readmitted and in-hospital babies who underwent exchange transfusion.

VariableReadmitted babies (total 26) In-hospital babies (total 38) value

Male gender ( (%))17 (65.4)20 (52.6)0.45
Birth weight (Kg) (mean (SD))2.7 (0.6)2.1 (0.9)<0.01
Gestational age (weeks) (mean (SD))37.3 (2.4)34.7 (4.9)0.01
Vaginal delivery ( (%))18 (69.4)19 (50)0.19
Signs of kernicterus ( (%))6 (23.1)NA
Total bilirubin before ET mol/L (mean (SD))507.4 (127.8)394.9 (140.2)<0.01
Breastfed ( (%))20 (76.9)16 (42.1)0.01
Age at ET (days) (mean (SD))4.6 (2.3)3.3 (2.2)0.03
Second ET ( (%))2 (7.6)1 (1.5)0.77
Intravenous immune globulin1 (3.6)0
Positive blood cultures ( (%))7 (26.9)5 (13.1)0.28
 Gram negative2/7 (28.5%)2/5 (40%)
 Gram positive5/7 (71.4%)3/5 (60%)0.57
Cause of hyperbilirubinemia ( (%))
 Isoimmune haemolysis6 (23.1)3 (7.8)
 ABO incompatibility2 (7.6)1 (2.6)
 Rh incompatibility4 (15.3)2 (5.2)
 Cephalhaematoma1 (3.6)00.09
 Red cell membranopathy01 (2.6)
 Severe intraventricular haemorrhage02 (5,2)
Complications of ET ( (%))
 Apnoea requiring mechanical ventilation1 (3.6)2 (5.2)
 Glucose instability02 (5.2)
Died03 (7.8)0.18