Table of Contents
International Scholarly Research Notices
Volume 2016 (2016), Article ID 7294274, 4 pages
http://dx.doi.org/10.1155/2016/7294274
Research Article

Primary Hyperparathyroidism and Pancreatitis: A Rare Association with Multiple Facets

1Department of Internal Medicine and Hepato-Gastroenterology, Hôpital Principal de Dakar, Dakar, Senegal
2Department of Medical Imaging, Hôpital Principal de Dakar, Dakar, Senegal
3Department of Biology, Hôpital Principal de Dakar, Dakar, Senegal

Received 27 July 2016; Accepted 6 September 2016

Academic Editor: Raffaele Pezzilli

Copyright © 2016 I. Diallo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Primary hyperparathyroidism (PHPT) is rarely associated with the occurrence of acute or chronic pancreatitis. Hypercalcemia plays a major role in the pathogenesis. We report five cases of pancreatitis revealing PHPT. Patients and Methods. This is a retrospective study of 4 years, including all patients admitted to intensive care unit or gastroenterology department, for an acute or chronic pancreatitis revealing primary hyperparathyroidism. Results. We included 5 patients, all female, with mean age 54 years [40–76 years]. The PHPT was in all cases revealed by acute pancreatitis (AP). This one was oedematous in four cases and severe in one case. It occurred twice in calcified chronic pancreatitis (CCP). There was hypercalcemia in all cases. The PHPT was associated with a high rate of parathyroid hormone in 4 cases. The secreting lesion was an adenoma in 5 cases. Two patients had in addition bilateral renal calcifications. The outcome was favorable in 4 patients among whom 3 have had parathyroid surgery. A death was noted by superinfection of necrosis in the case of severe AP. Conclusion. The occurrence of pancreatitis during hyperparathyroidism is rare. Normal or elevated calcemia during acute or chronic pancreatitis should always get attention.