Table of Contents
International Scholarly Research Notices
Volume 2017 (2017), Article ID 6463139, 5 pages
https://doi.org/10.1155/2017/6463139
Research Article

Sapium ellipticum (Hochst.) Pax Ethanol Leaf Extract Maintains Lipid Homeostasis in Streptozotocin-Induced Diabetic Rats

1Department of Biochemistry, Faculty of Sciences, Lead City University, Ibadan, Nigeria
2Department of Biochemistry, College of Biosciences, Federal University of Agriculture, Abeokuta (FUNAAB), Abeokuta, Nigeria
3College of Veterinary Medicine, Federal University of Agriculture, Abeokuta (FUNAAB), Abeokuta, Nigeria

Correspondence should be addressed to Osasenaga Mcdonald Ighodaro

Received 1 March 2017; Accepted 15 May 2017; Published 7 June 2017

Academic Editor: Marie Aleth Lacaille-Dubois

Copyright © 2017 Osasenaga Mcdonald Ighodaro et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. P. F. Dullaart, “Plasma lipoprotein abnormalities in type 1 (insulin-dependent) diabetes mellitus,” Netherlands Journal of Medicine, vol. 46, no. 1, pp. 44–54, 1995. View at Publisher · View at Google Scholar · View at Scopus
  2. B. Vergès, “Insulinosensibilité et lipids,” Diabetes & Metabolism, vol. 27, pp. 223–227, 2000. View at Google Scholar
  3. A. Chait and J. D. Brunzell, “Diabetes, lipids and atherosclerosis,” Textbook of Endocrinology, vol. 1, pp. 946-947, 1996. View at Google Scholar
  4. A. Shirwaikar, K. Rajendran, C. D. Kumar, and R. Bodla, “Antidiabetic activity of aqueous leaf extract of Annona squamosa in streptozotocin-nicotinamide type 2 diabetic rats,” Journal of Ethnopharmacology, vol. 91, no. 1, pp. 171–175, 2004. View at Publisher · View at Google Scholar · View at Scopus
  5. O. M. Ighodaro and J. O. Omole, “Effects of Nigerian Piliostigma thonningii Species leaf extract on lipid,” ISRN Pharmacology, 2012. View at Google Scholar
  6. A. H. Adebayo, R. Aliyu, D. Gatsing, and I. H. Garba, “The effects of ethanolic leaf extract of Commiphora africana (Buseraceae) on lipid profile in rats,” International Journal of Pharmacology, vol. 2, no. 6, pp. 618–622, 2006. View at Publisher · View at Google Scholar · View at Scopus
  7. C. Pérez, J. R. Canal, J. E. Campillo, A. Romero, and M. D. Torres, “Hypotriglyceridaemic activity of Ficus carica leaves in experimental hypertriglyceridaemic rats,” Phytotherapy Research, vol. 13, no. 3, pp. 188–191, 1999. View at Publisher · View at Google Scholar · View at Scopus
  8. A. Cignarella, M. Nastasi, E. Cavalli, and L. Puglisi, “Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate,” Thrombosis Research, vol. 84, no. 5, pp. 311–322, 1996. View at Publisher · View at Google Scholar · View at Scopus
  9. W. H. Lewis, “The useful plants of west tropical Africa,” in Royal Botanic Gardens, vol. 1, pp. 258-259, 2 edition, 1985, Kew. View at Publisher · View at Google Scholar
  10. G. E. Wickens and H. M. Burkill, “The useful plants of west tropical Africa,” Royal Botanic Gardens, Kew, vol. 1–3, no. 2, pp. 471-472, 1995. View at Publisher · View at Google Scholar
  11. S. A. Adesegun, N. A. Elechi, and H. A. B. Coker, “Antioxidant activities of methanolic extract of sapium ellipticum,” Pakistan Journal of Biological Sciences, vol. 11, no. 3, pp. 453–457, 2008. View at Publisher · View at Google Scholar · View at Scopus
  12. A. Sowemimo, M. ven de Venter, L. Baatjies, and T. Koekemoer, “Cytotoxicity evaluation of selected Nigerian plants used in traditional cancer treatment,” Journal of Medicinal Plants Research, vol. 5, no. 11, pp. 2442–2444, 2011. View at Google Scholar · View at Scopus
  13. O. Nana, J. Momeni Nzangué, R. Tepongning, M. B. Ngassoum, and J. Momeni Nzangué, “Phythochemical screening, antioxIdant and antiplasmodial activities of extracts from Trichilia roka and Sapium ellipticum,” The Journal of Phytopharmacology, vol. 2, pp. 22–29, 2013. View at Google Scholar
  14. A. Edimealem, P. Reneela, and J. Tsegaye, “Phytochemical investigation of Sapium ellipticum,” Natural Products and Plant Resources, vol. 3, pp. 1–6, 2013. View at Google Scholar
  15. N. Rakieten, M. L. Rakieten, and M. V. Nadkarni, “Studies on the diabetogenic action of streptozotocin (NSC-37917),” Cancer Chemotherapy, vol. 29, pp. 91–102, 1963. View at Google Scholar · View at Scopus
  16. NIHPublication., http://www.win.niddk.nih.gov.
  17. W. M. Buttler, H. M. Maling, M. G. Horning, and B. B. Brodie, “The direct determination of liver triglycerides,” Journal of Lipid Research, vol. 2, pp. 95-96, 1961. View at Google Scholar
  18. A. Sofowora, “Medicinal plants and Traditional Medicine in Africa,” in Spectrum Books, Ibadan, Nigeria, 2008. View at Google Scholar
  19. H. O. Edeoga, D. E. Okwu, and B. O. Mbaebie, “Phytochemical constituents of some Nigerian medicinal plants,” African Journal of Biotechnology, vol. 4, no. 7, pp. 685–688, 2005. View at Publisher · View at Google Scholar · View at Scopus
  20. G. E. Trease and W. C. Evans, in A textbook of Pharmacognosy, vol. 14, p. 832, Bailliere Tindall, London, 1996.
  21. J. B. Harborne, Phytochemical Methods, Chapman and Hall, New York, 2nd edition, 1984. View at Publisher · View at Google Scholar
  22. R. Ananthan, M. Latha, K. M. Ramkumar, L. Pari, C. Baskar, and V. N. Bai, “Effect of Gymnema montanum leaves on serum and tissue lipids in alloxan diabetic rats,” Experimental Diabesity Research, vol. 4, no. 3, pp. 183–189, 2003. View at Publisher · View at Google Scholar · View at Scopus
  23. T. Jensen, K. Borch-Johnsen, A. Kofoed-Enevoldsen, and T. Deckert, “Coronary heart disease in young Type 1 (insulin-dependent) diabetic patients with and without diabetic nephropathy: incidence and risk factors,” Diabetologia, vol. 30, no. 3, pp. 144–148, 1987. View at Publisher · View at Google Scholar · View at Scopus
  24. M.-R. Taskinen, “Quantitative and qualitative lipoprotein abnormalities in diabetes mellitus,” Diabetes, vol. 41, no. 2, pp. 12–17, 1992. View at Publisher · View at Google Scholar · View at Scopus
  25. O. A. Akinloye and O. O. Solanke, “Evaluation of hypolipidemic and potential antioxidant effects of Pigeon pea (Cajanus cajan) leaves in alloxan-induced hyperglycemic rats,” Journal of Medicinal Plants Research, vol. 5, pp. 2521–2524, 2011. View at Google Scholar · View at Scopus
  26. R. N. Ugbaja, B. O. Onunkwor, and D. A. Omoniyi, “Lead induced dyslipidemia: the comparative effects of ascorbate and chelation therapy,” African Journal of Biotchnology, vol. 12, pp. 1845–1852, 2012. View at Google Scholar
  27. A. A. Akindahunsi and S. O. Salawu, “Phytochemical screening and nutrient-antinutrient composition of selected tropical green leafy vegetables,” African Journal of Biotechnology<, vol. 4, pp. 563–568, 2005. View at Google Scholar · View at Scopus
  28. S. Tandon, “Phytochemicals and cardiovascular health“,” Current Highlights, vol. 28, pp. 18–22, 2005. View at Google Scholar
  29. H. P. Braun, “National cholesterol education programme. Recommendations for cholesterol measurements,” Chemistry, vol. 30, pp. 991–199, 1984. View at Google Scholar
  30. E. A. Stein and G. L. Myers, “National cholesterol education program recommendations for triglyceride measurement: Executive summary,” Clinical Chemistry, vol. 41, no. 10, pp. 1421–1426, 1995. View at Google Scholar · View at Scopus
  31. S. A. Grover, C. Levinton, and S. Paquet, “Identifying adults at low risk for significant hyperlipidemia: a validated clinical index,” Journal of Clinical Epidemiology, vol. 52, no. 1, pp. 49–55, 1999. View at Publisher · View at Google Scholar · View at Scopus
  32. M. Dobiasova, “AIPatherogenic index of plasma as a significant predictor of cardiovascular risk: from research to practice,” Vnitr Lek, vol. 52, pp. 64–71, 2006. View at Google Scholar
  33. D. B. Panagiotakos, C. Pitsavos, J. Skoumas et al., “Importance of LDL/HDL cholesterol ratio as a predictor for coronary heart disease events in patients with heterozygous familial hypercholesterolaemia: A 15-year follow-up (1987-2002),” Current Medical Research and Opinion, vol. 19, no. 2, pp. 89–94, 2003. View at Publisher · View at Google Scholar · View at Scopus