The Ethanolic Stem-Bark Extract of Antrocaryon micraster Inhibits Carrageenan-Induced Pleurisy and Pedal Oedema in Murine Models of Inflammation

Figure 4

Anti-oxidant effect of Antrocaryon micraster extract on carrageenan-induced pleurisy in rats. Sprague Dawley rats (200–250 g) were untreated or treated with either normal saline (5 ml/kg), diclofenac (10 mg/kg), or AME (30–300 mg/kg) p.o. for 3 days. Pleurisy was induced as described in the Methods. Lung homogenates were assayed for GSH (a), SOD (b), CAT (c), MPO (d), and MDA (e). Data is presented as mean ± SEM (). , , and compared to vehicle-treated control; and compared to naïve control (one-way ANOVA followed by Dunnett’s post hoc test).

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