Table of Contents
International Scholarly Research Notices
Volume 2017, Article ID 7052583, 5 pages
Review Article

Review of Organism Density and Bacteriologic Conversion of Sputum among Tuberculosis Patients

1Public Health Unit, Komfo Anokye Teaching Hospital, Kumasi, Ghana
2Research and Development Unit, Komfo Anokye Teaching Hospital, Kumasi, Ghana
3Department of Child Health, Komfo Anokye Teaching Hospital, Kumasi, Ghana
4Kumasi Centre for Collaborative Research in Tropical Medicine, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana

Correspondence should be addressed to Francis Adjei Osei; moc.liamtoh@1hpsicnarf

Received 23 March 2017; Revised 1 June 2017; Accepted 14 June 2017; Published 11 July 2017

Academic Editor: Nikolaos G. Koulouris

Copyright © 2017 Francis Adjei Osei et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. This study sought to describe the trend of sputum organism density and the rate of bacteriological conversion among smear positive TB patients assessing care at the Komfo Anokye Teaching Hospital (KATH), Kumasi, Ghana. Methods. We conducted a retrospective patient folder review from January 2013 to March 2016 at the KATH, a tertiary hospital in Ghana. The data was entered into Microsoft Access database and exported into STATA for analysis. We applied basic descriptive statistics to study variables. Sputum conversion rate (SCR) was estimated using the number of negative tests recorded over a period (numerator) and the number of patients reported in the same period (denominator) and expressed as a percentage. Results. A total of 278 patient records with sputum smear positive at onset were studied. Before treatment sputum density detected in smear microscopy was as follows: 1 acid-fast bacillus (+) (), scanty (), ++ (), and +++ (). We recorded sputum conversion rate of 80.90%, 94.56%, and 98.31% in the intensive, continuation, and completion phases, respectively. Conclusion. This study has shown an increasing trend in sputum conversion of smear positive pulmonary tuberculosis and an increasing trend in loss to follow-ups among tuberculosis patients on treatment.