Journal of Allergy / 2009 / Article / Tab 1

Research Article

Sex Disparity in Food Allergy: Evidence from the PubMed Database

Table 1

Sex disparity in food allergy reporting: implications for clinical and translational research.

Findings from our researchQuestions to consider

In children:- Does maternal imprinting and/or epigenetic modification differentially target sex in-utero with regard to food allergy?
Greater than 64% of the reported food allergies to 11 major foods involve boys- Is there a difference in exposure to allergenic foods among males and females?
- Is there a sex disparity in neonatal/postnatal immune response to allergenic foods?
- Is there a sex disparity in the quality (intensity and/or frequency) of clinical response to allergenic foods upon re-exposure among children?

In adults:- Is there a sex disparity in the outgrowing of food allergy during late childhood or adulthood?
Greater than 65% of the reported food allergies to 11 major foods involve women- Is there a difference in exposure to allergenic foods among males and females?
- What is the impact of the menstrual cycle, pregnancy, and sex hormones on allergic response to foods?
- Is there a sex disparity in the quality (intensity and/or frequency) of clinical response to allergenic foods upon re-exposure?
- Do psychosocial factors contribute to sex disparity in food allergy reporting?
- Does the sex disparity reflect a difference in food allergy or sensitization to aeroallergens resulting in oral allergy syndrome?

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