Research Article

Towards Defining Molecular Determinants Recognized by Adaptive Immunity in Allergic Disease: An Inventory of the Available Data

Table 1

Overview of allergy epitope data included in the IEDB.

CategoryTotal number

References678
Epitopes (positive structures)4,800
Negative structures4,137
Antibody/B cell3,194
 Linear natural peptides2,730
 Linear analogs/no natural source163
 Discontinuous determinants65
T cell1,646
 CD4+/Class II1,530
 CD8+/Class I17
 Unspecified99
Unique allergens (peptidic/nonpeptidic)550
Source species88
Food allergy epitopes2,322 (53%)
Airborne allergy epitopes1,750 (40%)
Stinging insects epitopes127 (3%)
Drug allergy epitopes106 (~2%)
Contact allergy epitopes82 (~2%)