Research Article
Allergic Potential and Immunotoxicity Induced by Topical Application of 1-Chloro-4-(Trifluoromethyl)Benzene (PCBTF) in a Murine Model
Table 1
Phenotypic analysis after in vivo PCBTF treatment.
| Dose group | IgE+B220+ (% lymphocyte population) | B220+ (% lymphocyte population) | | % | Cells × 106 | % | Cells × 106 |
| DLN | | | | | Acetone | 1.1 ± 0.3 | 0.09 ± 0.02 | 11.5 ± 1.9 | 1.1 ± 0.16 | PCBTF | | | | | 50% | 4.5 ± 2.1 | 0.13 ± 0.02 | 14.0 ± 3.1 | 2.0 ± 0.53 | 75% | 3.5 ± 0.4 | 0.12 ± 0.02 | 12.6 ± 0.9 | 1.8 ± 0.24 | 100% | 2.4 ± 0.6 | 0.14 ± 0.01 | 12.0 ± 1.4 | 1.8 ± 0.23 |
| Spleen | | | | | Acetone | 4.2 ± 2.4 | 2.1 ± 1.01 | 43.4 ± 4.7 | 2.3 ± 1.06 | PCBTF | | | | | 50% | 4.7 ± 2.5 | 2.2 ± 1.33 | 38.9 ± 1.8 | 1.7 ± 1.12 | 75% | 1.4 ± 0.1 | 1.7 ± 1.58 | 42.6 ± 1.7 | 1.9 ± 0.96 | 100% | 2.2 ± 0.9 | 2.1 ± 0.98 | 40.1 ± 1.4 | 2.1 ± 1.21 |
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