Table of Contents
Journal of Allergy
Volume 2011, Article ID 547389, 2 pages
Case Report

Lability of IgE Levels Early in Life

Koffi N'guessan,1,2,3,4,5 David Ternant,2,3,4,6 François Labarthe,3,7,8 and Hervé Watier1,2,3,4

1Laboratoire d'Immunologie Faculté de Médecine, 10 Boulevard Tonnellé, 37032 Tours Cedex, France
2Pilot Center for Therapeutic Antibody Monitoring, CHRU de Tours, France
3Université François-Rabelais de Tours, France
4CNRS, UMR6239, France
5Faculté de Médecine d'Abidjan, Cote D'Ivoire
6Laboratories of Pharmacology, CHRU de Tours, France
7Pediatric Department, CHRU de Tours, France
8INSERM, U921, France

Received 21 February 2011; Accepted 28 April 2011

Academic Editor: Robert A. Wood

Copyright © 2011 Koffi N'guessan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We report a case of a very fast and intriguing decrease in IgE concentrations after exclusion from the diet of any CM lysate in an unusual clinical presentation of cow's milk allergy in an infant. Analysis of IgE kinetics after allergen elimination suggests rapid cessation of IgE biosynthesis and a short IgE half-life.