Is There a Regulatory Role of Immunoglobulins on Tissue Forming Cells Relevant in Chronic Inflammatory Lung Diseases?

Figure 2

Epithelial cells express IgE and IgG receptors and respond directly to the respective immunoglobulins. Suggested (dashed line) and proven intracellular signaling pathways in human and animal airway epithelial cells. Importantly the IgG receptor expressed on airway epithelial cells may enable antigens to path un-changed through the epithelium and then contact with subepithelial mesenchymal cells [77].