Table of Contents
Journal of Allergy
Volume 2011, Article ID 751052, 12 pages
http://dx.doi.org/10.1155/2011/751052
Research Article

Inhalation of Ortho-Phthalaldehyde Vapor Causes Respiratory Sensitization in Mice

1Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV 26505-2888, USA
2Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV 26505-2888, USA

Received 22 February 2011; Accepted 27 April 2011

Academic Editor: Gordon L. Sussman

Copyright © 2011 Victor J. Johnson et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Numerical data for cytokine mRNA expression levels (Table S1) and lymph node immunophenotyping (Table S2). Mice were exposed to OPA (125, 250, 500, 1000 ppb) or filtered air according to the schedule shown in Figure 1. Two days following the final exposure, the mandibular lymph nodes (left side), nasal mucosa and lungs were removed and processed for gene expression analysis (Table S1). Lymph nodes from the right side were removed and processed into single cell suspensions and labeled for immunophenotyping according to the Methods section (Table S2).

  1. Supplementary Material