The Contribution of Allergen-Specific IgG to the Development of Th2-Mediated Airway Inflammation

Figure 2

Mouse and human FcγR structure diagram. Receptors are labeled as “activating,” “inhibitory,” or “unknown.” Relative affinity of each receptor to monomeric (free) IgG is listed below each receptor [12, 16]. Signaling chains associated with each receptor are labeled; beige diamonds represent ITAMs, green box represents ITIM, and grey box represents cell membrane.