Review Article

How Can Microarrays Unlock Asthma?

Table 2

Asthma-related phenotypes that result from aberrant expression of splice variants.

SymbolGene NamePhenotypesDescriptionReference

NPSR1neuropeptide S receptor 1IgE levels and AsthmaIsoform B over expressed in asthmatic ASM cells[15]
IL-4interleukin-4AsthmaAlternatively spliced variants of IL-4 mRNA are differently expressed in patients with bronchial asthma[58, 59]
COX-1cytochrome c oxidase assembly homolog (yeast)AsthmaAlternatively spliced variants of COX-1 mRNA are differently expressed in patients with bronchial asthma[60]