IgE-Mediated Anaphylaxis to Foods, Venom, and Drugs: Influence of Serum Angiotensin Converting Enzyme Levels and Genotype

Table 4

Odds ratio analysis of genotype comparison with DD genotype.

Comparisons with DD	Odds ratio (95% CI)	Odds ratio (95%CI)	Chi square 𝑃-value
	ID	II
Relative to healthy controls (𝑛=119)
Atopies (𝑛=49)	2.3 (1.0–5.4)	1.4 (0.4–4.1)	0.082
Anaphylaxis (𝑛=120)	3.3 (1.7–6.3)	3.1 (1.4–6.9)	<0.001
CRA (𝑛=27)	1.1 (0.4–2.9)	0 (0–0.7)	0.051
AACVS (𝑛=93)	6.3 (2.7–15.3)	7.5 (2.9–19.8)	<0.001
Relative to atopic subjects (𝑛=49)
Anaphylaxis (𝑛=120)	1.4 (0.6–3.3)	2.3 (0.7–7.3)	0.24
CRA (𝑛=27)	0.5 (0.2–1.5)	0 (0–0.5)	0.028
AACVS (𝑛=93)	2.7 (1.0–7.7)	5.4 (1.5–19.5)	0.009
Relative to CRA (𝑛=27)
AACVS (𝑛=93)	5.6 (1.8–17.4)	44 (5–1891)*	<0.001

*calculated by adding 1 to each cell, biased towards 1.