Research Article
Cyclin D1 in ASM Cells from Asthmatics Is Insensitive to Corticosteroid Inhibition
Table 1
Subject demographics.
| Subject no. | Gender | Disease | FEV1 (% Pred) | FVC (% Pred) | FEV1 : FVC (%) | Smoker | Height | Weight | Experiments |
| 1 | F | Ca | | | | | | | 1, 2 | 2 | F | A | 64% | 70% | 76% | Ex-smoker | | | 1, 3 | 3 | F | Ca | | | | | | | 1, 2 | 4 | M | A | 82% | | | No | | | 1, 3 | 5 | F | NSCCa | | | | Yes | | | 1, 2 | 6 | F | A | 2.04 L | 2.5 L | | No | 158 cm | 64 kg | 1, 3 | 7 | M | NSSCa | 2.12 L | 3.35 L | | Ex-smoker | 173 cm | 76 kg | 1, 2 | 8 | F | A | 1.87 L | 2.32 L | | No | 168 cm | 57 kg | 1, 3 | 9 | F | Bronchiolitis obliterans | | | | | | | 1, 2 | 10 | M | A | 3.75 L | 5.9 L | | No | 179 cm | 110 kg | 1, 3 | 11 | M | Emphysema | | | | | | | 1, 2 | 12 | M | A | | | | No | | | 1, 3 | 13 | F | Emphysema | | | | Yes | | | 1, 2 | 14 | M | A | 4.77 L | 5.32 L | | Yes | | | 1, 3 | 15 | F | Emphysema | 27% (0.51 L) | 67% (1.5 L) | | | 153 cm | | 1, 2 | 16 | M | Emphysema, α-1 antitrypsin deficiency | 15% (0.61 L) | 66% (3.42 L) | | | | | 4 | 17 | M | A | 57% | 61% | 77% | No | | | 4 | 18 | M | COPD | 20% | 65% | 24% | Yes | | | 4 | 19 | M | Ca + A | | | | Ex-smoker | | | 4 | 20 | M | Ca | 1.95 L | 2.5 L | | Ex-smoker | 169 cm | 79 kg | 4 | 21 | M | A | | | | | | | 4 |
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Abbreviations used: Ca, carcinoma; A, asthma; NSCCa, nonsmall cell carcinoma; COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 second (% predicted); FVC, forced vital capacity (% predicted).
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