Comparison of CD63 Upregulation Induced by NSAIDs on Basophils and Monocytes in Patients with NSAID Hypersensitivity

Table 2

Description of patients suffering from NSAID hypersensitivity.

Group of patients*		Age	Sex ratio	Atopy**	C/E IU***	HS ≥ 2**** NSAIDs
Grade I	𝑛=38	44	29F/9M	9 (24%)	18 (47%)	25 (66%)
Grade II	𝑛=22	43	16F/6M	7 (32%)	12 (55%)	17 (77%)
Total	𝑛=60	44	45F/15M	16 (27%)	30 (50%)	42 (70%)

*Patients with a history of urticaria or angiooedema and no visceral disorder were classified as having had a hypersensitivity of grade I and those with at least one visceral disorder were classified as grade II according to published works [18].
**Patients had history of atopic dermatitis, allergic rhinitis, or asthma, but they had healed at the time of NSAID hypersensitivity.
***The patients with “C/E IU” had chronic or episodic idiopathic urticaria or angiooedema; NSAID hypersensitivity was diagnosed when symptoms worsen relapsed, or were unusual and recovered when they stopped NSAID intake.
****Patients who had histories of hypersensitivity induced by at least two chemically distinct NSAIDs.