Research Article
The IL1B-511 Polymorphism (rs16944 AA Genotype) Is Increased in Aspirin-Exacerbated Respiratory Disease in Mexican Population
Table 3
Genotype frequencies of IL8 and IL1B genes in AERD, ATA, and HCS.
| | Gene/SNP Genotype | AERD | ATA | HCS | | GF (%) | | GF (%) | | GF (%) |
| | IL8 | | | | | | | | rs4073 | | | | | | | | AA | 35 | 0.449 (44.87) | 54 | 0.400 (40.00) | 53 | 0.396 (39.55) | | AT | 33 | 0.423 (42.31) | 57 | 0.422 (42.22) | 63 | 0.470 (47.01) | | TT | 10 | 0.128 (12.82) | 24 | 0.178 (17.78) | 18 | 0.134 (13.43) | | IL1B | | | | | | | | rs16944 | | | | | | | | GG | 23 | 0.295 (29.49) | 57 | 0.422 (42.22) | 47 | 0.351 (35.07) | | GA | 40 | 0.513 (51.28) | 68 | 0.504 (50.37) | 72 | 0.537 (53.73) | | AA | 15 | 0.192 (19.23) | 10 | 0.074 (7.41) | 15 | 0.112 (11.19) |
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AERD: Aspirin-exacerbated respiratory disease, ATA: aspirin-tolerant asthma, HCS: healthy control subjects, GF: genotype frequency.
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