Reticular Basement Membrane Vessels Are Increased in COPD Bronchial Mucosa by Both Factor VIII and Collagen IV Immunostaining and Are Hyperpermeable
Figure 1
Vessels in the bronchial mucosa. Bronchial biopsies taken from the same current-smoking COPD subject, ×400. Vessels (black arrows) are stained with anti-Collagen IV antibody (a) and anti-Factor VIII antibody (b). A large vessel which contacts the reticular basement membrane (Rbm, arrowheads) is indicated by white arrows. The epithelium is thickened, probably because of chronic smoking exposure.