Impact of Adiponectin Overexpression on Allergic Airways Responses in Mice

Figure 2

Leukocytes in BAL fluid (a) and blood (b) and BAL IL-13 (c), BAL eotaxin (d), and serum OVA-specific IgE (e) of wildtype (WT) and adiponectin transgenic (Adipo Tg) mice sensitized with ovalbumin (OVA) and exposed to aerosols of OVA or PBS. Data shown are mean ± SEM of 5-6 PBS and 9-10 OVA treated mice per group except for OVA-specific IgE (𝑛=5-6 for PBS and 12-13 for OVA). ^∗𝑃<0.05 versus PBS challenged mice of the same genotype; ^#𝑃<0.05 versus WT mice with the same exposure. MAC: macrophages; NEU: neutrophils; EOS: eosinophils; LYM: lymphocytes; MON: mononuclear cells.

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