Journal of Allergy

Crosstalk between Innate and Adaptive Cells on Allergic Process


Publishing date
26 Oct 2012
Status
Published
Submission deadline
08 Jun 2012

Guest Editors

1CNRS UMR 8147, Université Paris V, Paris, France

2Laboratory of Immunoregulation, Department of Pulmonary Medicine, University Hospital Gent, 9000 Gent, Belgium

2CNRS UMR 8147, Université Paris V, Paris, France


Crosstalk between Innate and Adaptive Cells on Allergic Process

Description

Allergies have increased dramatically in prevalence and severity over the past two decades. It was reported that adaptive immunity plays a critical role in the pathogenesis of this disease. Nevertheless, the implication of innate immune response and the interaction between cells from innate and adaptive immunity, that will finally determine the severity of the allergic process, remain poorly understood. In addition, there is compelling evidence that epithelial cells could license innate and adaptive immune responses at mucosal sites. The presence of distinct immune cell types conjointly to the local production of a triad of cytokines as TSLP (thymic stromal lymphopoietin), IL-13, IL-17, IL-22, IL-23, and IL-33 highlights the complexity of the allergic responses. Consequently, we invite authors to submit original research and review articles that seek to understand the crosstalk between innate and adaptive immune responses in allergic process. We are interested in articles that explore these mechanisms in humans and animal models. Potential topics include, but are not limited to:

  • Role of recently described innate cells as nuocytes and innate lymphoid cells on the development of allergic responses
  • Getting insight into the crosstalk between dendritic cells, basophils, mast cells, neutrophils, eosinophils, Natural Killer T cells, and conventional T and B lymphocytes on the immunological mechanisms resulting in allergy
  • Elucidating the impact of epithelial cell dysfunction on both innate and adaptive immunity in allergy
  • New hypothesis to explain the development of allergic process observed in allergic asthma, contact, and food allergy taking in consideration epithelial cells, immune cells, and microbial antigens
  • Determining the implication of innate cells on the induction of allergen immunotherapy
  • Development of new immunotherapeutic strategies to treat seasonal or chronic allergy

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ja/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 720568
  • - Editorial

Crosstalk between Innate and Adaptive Cells on Allergic Process

Maria Leite-de-Moraes | Hamida Hammad | Michel Dy
  • Special Issue
  • - Volume 2012
  • - Article ID 245909
  • - Research Article

Neutrophil Inhibitory Factor Selectively Inhibits the Endothelium-Driven Transmigration of Eosinophils In Vitro and Airway Eosinophilia in OVA-Induced Allergic Lung Inflammation

Silvia Schnyder-Candrian | Isabelle Maillet | ... | René Moser
  • Special Issue
  • - Volume 2012
  • - Article ID 176468
  • - Review Article

Lung Dendritic Cell Developmental Programming, Environmental Stimuli, and Asthma in Early Periods of Life

Shanjana Awasthi | Bhupinder Singh | ... | Rodney R. Dietert
  • Special Issue
  • - Volume 2012
  • - Article ID 718725
  • - Review Article

Keratinocytes under Fire of Proinflammatory Cytokines: Bona Fide Innate Immune Cells Involved in the Physiopathology of Chronic Atopic Dermatitis and Psoriasis

François-Xavier Bernard | Franck Morel | ... | Jean-Claude Lecron
  • Special Issue
  • - Volume 2012
  • - Article ID 236075
  • - Review Article

The Contribution of Allergen-Specific IgG to the Development of Th2-Mediated Airway Inflammation

Jesse W. Williams | Melissa Y. Tjota | Anne I. Sperling
  • Special Issue
  • - Volume 2012
  • - Article ID 948901
  • - Review Article

Regulatory T Cells and the Control of the Allergic Response

Ana Agua-Doce | Luis Graca