Review Article
The Aggregation Inhibitor Peptide QBP1 as a Therapeutic Molecule for the Polyglutamine Neurodegenerative Diseases
Table 1
Polyglutamine binding peptides isolated from phage display screening.
| Name | Q62/Q19 binding ratio | Sequence (X5-fixed-X5) |
| QBP1 | 1.66 | Ser-Asn-Trp-Lys-Trp-Trp-Pro-Gly-Ile-Phe-Asp | QBP2 | 1.31 | His-Trp-Trp-Arg-Ser-Trp-Tyr-Ser-Asp-Ser-Val | QBP3 | 1.30 | His-Glu-Trp-His-Trp-Trp-His-Gln-Glu-Ala-Ala | QBP4 | 1.27 | Trp-Gly-Leu-Glu-His-Phe-Ala-Gly-Asn-Lys-Arg | QBP5 | 1.25 | Trp-Trp-Arg-Trp-Asn-Trp-Ala-Thr-Pro-Val-Asp | QBP6 | 1.23 | Trp-His-Asn-Tyr-Phe-His-Trp-Trp-Gln-Asp-Thr | SCR | | Trp-Pro-Ile-Trp-Ser-Lys-Gly-Asn-Asp-Trp-Phe |
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