The Aggregation Inhibitor Peptide QBP1 as a Therapeutic Molecule for the Polyglutamine Neurodegenerative Diseases

Table 2

Examples of protein transduction domains.

Name	Origin/design	Sequence
TAT	HIV-1 transactivator	Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg
Antp	Drosophila Antennapedia	Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met- Lys-Trp-Lys-Lys
VP22	HSV-1 structural protein	Asp-Ala-Ala-Thr-Ala-Thr-Arg-Gly-Arg-Ser-Ala-Ala-Ser-Arg-Pro-Thr-Glu-Arg-Pro-Arg-Ala-Pro-Ala-Arg- Ser-Ala-Ser-Arg-Pro-Arg-Arg-Pro-Val-Asp
Polyarginine	Synthetic	(Arg)𝑛
Transportan	Neuropeptide galanin + wasp peptide mastoparan	Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Lys-Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys- Lys-Ile-Leu