Metal Preferences of Zinc-Binding Motif on Metalloproteases

Figure 1

The superimposition of the active sites of rat DPP III and thermolysin. Zinc ion is shown as a green sphere, and amino acid side chains are shown as sticks colored red for oxygen and blue for nitrogen. Metal coordinates in light blue and hydrogen bonds in yellow are indicated by dashed lines. Carbon atom and amino acid chain are shown colored white for thermolysin and magenta for DPP III. Metal coordination bonds are indicated by light blue dashed lines.