Long-Lasting Effects of Oxy- and Sulfoanalogues of L-Arginine on Enzyme Actions

Table 2

Total energies of the complexes and fitness function values of bis(adenosine)-5′-tetraphosphate with ADK and mutated ADK.

Mutation	Total energy of the complex	Fitness function value
Without any mutation Arg138 and Arg175	−135.483	69.29
Cav138, Arg175	−112.329	68.08
NCav138, Arg175	−147.651	90.30
sArg138, Arg175	−102.358	97.74
Arg138, Cav175	−128.855	68.08
Arg138, NCav175	−127.472	93.76
Arg138, sArg175	−131.506	96.24