Immune Activation and Inflammation in Patients with Cardiovascular Disease Are Associated with Higher Phenylalanine to Tyrosine Ratios: The Ludwigshafen Risk and Cardiovascular Health Study
Table 2
Spearman's rank correlations of investigated characteristics ().
Phenylalanine to tyrosine ratio versus
Spearman's rank correlations value (95% confidence interval)
value
Neopterin
0.216 (0.159–0.271)
<0.0001
hsCRP
0.122 (0.064–0.179)
<0.0001
ACS score
0.100 (0.042–0.157)
0.0005
Age
0.098 (0.040–0.156)
0.0007
CAD score
0.048 (−0.011–0.106)
n.s.
HDL-cholesterol
−0.010 (−0.068–0.049)
n.s.
Metabolic syndrome score
−0.016 (−0.074–0.043)
n.s.
Triglycerides
−0.034 (−0.092–0.025)
n.s.
LDL-cholesterol
−0.040 (−0.098–0.019)
n.s.
Total cholesterol
−0.045 (−0.103–0.014)
n.s.
Systolic blood pressure
−0.058 (−0.116–0.000)
0.0434
Daily smoked cigarettes
−0.059 (−0.117–−0.001)
0.0412
Diastolic blood pressure
−0.110 (−0.167–−0.051)
0.0001
BMI
−0.135 (−0.192–−0.077)
<0.0001
GFR
−0.264 (−0.318–−0.209)
<0.0001
GFR: glomerular filtration rate, hsCRP: high sensitivity C-reactive protein, and n.s.: not significant; coronary artery disease (CAD) score: 0: no CAD; 1: 11 to 49% stenosis; 2: one vessel disease; 3: two- or three-vessel disease; acute coronary syndrome (ACS) score: 0: no ACS; 1: unstable angina pectoris; 2: NSTEMI; 3: STEMI.
